中文摘要:
作为镧系元素(Ln)之一的稀土钆(Gd),由于原子序数大、最外层电子未成对且电子诱导能力不同,使其具有丰富的物理化学性质,吸引了广大研究者的兴趣,尤其是在生物医学领域.对钆元素在磁共振成像(MRI)、荧光成像、抗菌作用以及放射增敏的抗肿瘤作用方面进行了综述,以进一步促进钆元素在生物医学上的研究和运用.
中文关键词: 钆(Gd) 磁共振成像 荧光成像 抗菌 放射增敏治疗
DOI:10.3969/J.ISSN.1000-5137.2019.06.004
基金项目: 国家自然科学基金(21601124)
Application of rare earth gadolinium in biomedicine
WANG Shenjun, LI Yaping, TIAN Qiwei College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
Abstract:
Gadolinium(Gd),one of the lanthanides(Ln),exhibits a variety of physical and chemical properties due to its large atomic number,unpaired outer electrons,and different electron inducing ability,which has attracted great attention,especially in biomedicine.Hence,the applications of Gd in the magnetic resonance imaging(MRI),fluorescence imaging,antibacterium,and radiation-sensitized tumor therapy were reviewed in this paper to further promote the research and application of Gd in biomedicine.
Key words: gadolinium(Gd) magnetic resonance imaging(MRI) fluorescence imaging antibacterium radiation-sensitized tumor therapy